Zitat:Abteilung Klinische Psychologie und Psychotherapie, Georg-Elias-Müller-Institut für Psychologie der Georg-August-Universität Göttingen:
Dipl.-Psych. Gaßmann, Dipl.-Psych. Dr. rer. nat. Vath, van Gessel, MSc, Dipl.-Psych. Prof. Dr. phil. Kröner-Herwig............

Zitat:Partial idiopathic epilepsy: recovery after allergen-free diet.
Frediani T, Pelliccia A, Aprile A, Ferri E, Lucarelli S.
Department of Pediatrics, La Sapienza, University of Rome. frediani@uniroma1.it
The hypothesis that certain foods or allergens might bring about convulsions has been suggested repeatedly in the literature over the last century. Some clinical studies have highlighted an unusually high prevalence of allergic disorders in patients with epilepsy. This paper reports the consistent disappearance of partial idiopathic epilepsy symptoms in a nine-year-old patient as a result of diet free of cow's milk protein. This case appears to confirm the possible role of food allergy in certain types of epilepsy in patients of pediatric age.
PMID: 16366404 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/16366...d_RVDocSum

Zitat:Partial cryptogenetic epilepsy and food allergy/intolerance. A causal or a chance relationship? Reflections on three clinical cases.
Pelliccia A, Lucarelli S, Frediani T, D'Ambrini G, Cerminara C, Barbato M, Vagnucci B, Cardi E.
Neurological and Psychiatric Sciences Department, University of Rome, La Sapienza.
The possibility that certain foods or allergens may induce convulsions has already been reported in the literature. None of these studies has, however, shown a close correlation between food allergy and epilepsy, most reports being anecdotal and open to various aetiological hypotheses. The present report concerns 3 children with cryptogenetic partial epilepsy, diagnosed by means of electroencephalography, with behavioural disorders (hyperactivity, sleep disorders and writing difficulties). In these patients, instead of using anticonvulsive agents, treatment was based upon a cows milk-free diet, working on the hypothesis that there could be a casual relationship between intolerance to this food item and the epileptic symptoms. An improvement was observed in the children's behaviour and moreover, the electroencephalographic anomalies disappeared. Upon double blind oral provocation tests, these patients did not present an immediate reaction, but only after a few days. starting the controlled diet again led, in all cases, to disappearance of the electroencephalogram. In conclusion, it would appear feasible to hypothesize the role of food intolerance in the onset of convulsive crises, even if limited to certain types of epilepsy such as the cryptogenetic partial form.
PMID: 10479881 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/10479...edarticles

Zitat: Allergy and childhood epilepsy: a close relationship?

Frediani T, Lucarelli S, Pelliccia A, Vagnucci B, Cerminara C, Barbato M, Cardi E.

Department of Paediatrics, University of Rome La Sapienza, Italy. tufredi@tin.it

OBJECTIVES: The possibility that certain foods or allergens may induce convulsions has already been reported in the literature. None of the relevant studies has, however, shown a close correlation between allergy and epilepsy, most reports being anecdotal and open to various causal hypotheses. The case-control study reported here was undertaken to test the hypothesis that epilepsy is linked to allergy. MATERIAL AND METHODS: Seventy-two epileptic children and a group of 202 controls in the same age bracket were investigated for allergy together with their immediate families. RESULTS: The study revealed significantly higher rates of eczema in the mothers and rhinitis in the siblings of the patients studied as well as generally higher incidence of allergic pathologies in both of these groups with respect to the relevant controls. A significantly higher incidence of allergy to cow's milk and asthma was also documented in the epileptic children with respect to the control group. Prick tests gave a significantly higher rate of positive results for cow's milk proteins in the cases examined with respect to the controls. The total serum IgE of a random sample of cases and controls showed no difference in mean values. CONCLUSION: The study appears to bear out the hypothesis of a higher incidence of allergy in the children with epilepsy and their immediate families than in the controls and their families.

PMID: 11903088 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query...t=Abstract

Zitat:People with some medical conditions might be more likely to develop coeliac disease, for example Type 1 diabetes, thyroid problems, ulcerative colitis and certain neurological disorders, such as epilepsy.
http://www.medicalnewstoday.com/articles/8624.php

Zitat:Folgende Krankheiten sind häufig mit der Zöliakie assoziiert: Insulin – pflichtiger? Diabetes mellitus (2 – 4 %) (20, 56, 82, 147), Autoimmunerkrankungen der Schilddrüse (2 – 4 %) (20, 56, 82), selektiver IgA-Mangel (10%) (18, 82, 147), Sjögren`s Syndrom (3%) (20, 82, 147), rheumatische Erkrankungen (137), Alopecia areata (82), pulmonale Erkrankungen (20, 56), Lebererkrankungen (20, 56), entzündliche Darmerkrankungen (20, 56), Ullrich – Turner – Syndrom (8%) (147), Down – Syndrom (7%) (147).
Ebenfalls konnte eine große Anzahl an neurologischen Manifestationen, die nicht selten mit Zöliakie assoziiert sind, festgestellt werden, so zum Beispiel die Epilepsie (45, 56), cerebelläre Ataxie (8, 49), periphere Neuropathie (49), Myelopathie (49), Myopathie (49) und Demenz (49), aber auch psychiatrische Sörungen wie Depressionen und Angstzustände (56).
http://miami.uni-muenster.de/servlets/De...essing.pdf

Zitat:13: Allergy. 2005 Jul;60(7):912-9.
Humoral and cellular responses to cow milk proteins in patients with milk-induced IgE-mediated and non-IgE-mediated disorders.
Shek LP, Bardina L, Castro R, Sampson HA, Beyer K.
Division of Pediatric Allergy and Immunology and The Jaffe Institute for Food Allergy, The Mount Sinai School of Medicine, New York, NY 10029-6574, USA.

BACKGROUND: Cow milk allergy (CMA) is one of the most common food allergies in childhood. Patients with CMA present with a wide range of immunoglobulin (Ig)E- and non-IgE-mediated clinical syndromes. Limited information is known about the specific humoral and cellular responses to cow milk proteins in these various
forms of CMA. OBJECTIVE: The aim of the study was to determine IgE, IgA, IgG1 and IgG4 antibody levels and lymphocyte proliferative responses to the major cow milk allergens in patients with IgE- and non-IgE-mediated CMA. METHODS: One hundred and forty cow milk allergic patients, 6 months to 22 years of age, were included in the study. One hundred and thirteen patients had IgE-mediated CMA, 11 had milk protein-induced enterocolitis syndrome and 16 had allergic eosinophilic gastroenteritis. Twenty-one patients without food allergy, 8 months to 18 years of age, served as controls. Serum IgE, IgA, IgG1 and IgG4 antibodies to alpha-, beta-, and kappa-casein, alpha-lactalbumin and beta-lactoglobulin were measured using enzyme-linked immunosorbent assays. For a subset of these patients, we performed lymphocyte proliferation assays to the various milk allergens. RESULTS: Patients with IgE-mediated CMA had higher specific IgE concentrations to casein compared with whey proteins (P < 0.001). In this group of patients, there was a positive correlation between IgE levels and levels of the other isotypes for all four milk proteins (P < 0.001). In general, the caseins were the more allergenic and antigenic proteins in all groups of patients. Patients with enterocolitis syndrome produced less milk protein-specific IgG4 (P < 0.05) and had a trend for higher IgA antibody levels when compared to the control group. Lymphocyte proliferative responses in all groups with CMA were significantly higher than controls (P < 0.05), although this response was similar in patients with IgE- and non-IgE-mediated CMA. CONCLUSION: There is a distinct pattern of humoral antibody response in the different forms of CMA. Patients with IgE-mediated CMA have an elevated polyisotypic response to cow milk protein. The relative lack of specific IgG4 production in patients with enterocolitis syndrome may be involved in the pathogenesis of the disease. In general, caseins appear to be the predominant allergen in patients with CMA.
PMID: 15932382 [PubMed - in process]
http://www.blackwell-synergy.com/doi/abs...05.00705.x